Coco Gauff vs. Emma Raducanu—two former US Open champions—is a possible second-rounder, but only if the Brit gets past Moyuka Uchijima.
Defending Indian Wells champion and No. 2 seed Iga Swiatek will face either Caroline Garcia or Bernarda Pera.
And in one of the more tantalizing round-two possibilities, Zheng Qinwen, the WTA No. 9 and Olympic gold medalist, could face two-time Indian Wells champion Victoria Azarenka (or a TBD qualifier).—Ed McGrogan